The endocannabinoid system in canine Steroid-Responsive Meningitis-Arteritis and Intraspinal Spirocercosis

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منابع مشابه

The endocannabinoid system in canine Steroid-Responsive Meningitis-Arteritis and Intraspinal Spirocercosis

Endocannabinoids (ECs) are involved in immunomodulation, neuroprotection and control of inflammation in the central nervous system (CNS). Activation of cannabinoid type 2 receptors (CB2) is known to diminish the release of pro-inflammatory factors and enhance the secretion of anti-inflammatory cytokines. Furthermore, the endocannabinoid 2-arachidonoyl glycerol (2-AG) has been proved to induce t...

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BACKGROUND Steroid Responsive Meningitis-Arteritis (SRMA) is a common cause of inflammation of the canine central nervous system (CNS). To investigate if transforming growth factor beta 1 (TGF-β1), interleukin-6 (IL-6) and vascular endothelial growth factor (VEGF) are involved in the production of excessive immunoglobulin A (IgA), the induction of acute phase proteins and in the development of ...

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Canine spirocercosis.

Spirocercosis (Spirocerca lupi) in dogs has been mostly associated with the presence of esophageal granulomas that may transform to sarcomas; aortic aneurysms; mid-thoracic spondylitis; hypertrophic osteopathy; salivary gland necrosis; and pyothorax. Although the disease is frequently subclinical, esophageal dysphagia manifested by regurgitation, odynophagia, and hypersalivation is considered t...

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A Fatal Case of Acute Steroid Responsive Meningitis Arteritis in a Dog

Received: Revised: Accepted: September 12, 2011 November 15, 2011 February 12, 2012

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Canine spirocercosis-associated extraskeletal osteosarcoma with central nervous system metastasis.

A five-year-old male Boerboel presented for examination, collapsed for an unknown period of time. On clinical examination, multifocal subcutaneous masses and enlarged prescapular lymph nodes as well as neurological deficits that suggested a multifocal neurological syndrome were found. Fine needle aspirates of the prescapular lymph nodes revealed cells suggestive of osteosarcoma. Radiographs sho...

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ژورنال

عنوان ژورنال: PLOS ONE

سال: 2018

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0187197